습관적인 커피 섭취는 장내 미생물군을 형성하고 생리와 인지를 바꿈

This research demonstrates that habitual coffee consumption reshapes gut microbiota and influences cognitive and mood outcomes through the microbiota-gut-brain axis. The findings reveal that individual differences in polyphenol metabolism are mediated by the microbiome, highlighting coffee as a complex dietary modulator of brain function beyond direct caffeine effects. The temporal dynamics of coffee cessation and reintroduction provide evidence that these microbiota-dependent mechanisms are reversible and time-dependent.