rising4월 15일· 2 sources
Cracks in the Foundation: The Crisis Facing Alzheimer’s Amyloid Research
흔들리는 알츠하이머 연구의 근간: amyloid-β 가설을 둘러싼 위기와 불신
Why it matters
The recent retraction of foundational Alzheimer’s papers highlights a growing crisis in the 'amyloid hypothesis,' which has dominated the field for decades despite clinical failures. This shift necessitates a critical re-evaluation of dementia research as billions in drug development have failed to yield results based on this single protein.
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alzheimer'salzheimer's diseaseamyloid hypothesisamyloid-βbrain biologyclinical barriersdementiadrug developmentresearch progressresearch retraction